Intrinsically Disordered Biological Macromolecules in Cellular Signaling/Regulation

Registration (required): go.rutgers.edu/pc8prcsl

1:00–1:05 pm	Welcome and Introductions Stephen K. Burley, M.D., D.Phil., Rutgers Institute for Quantitative Biomedicine Steven K. Libutti, M.D., F.A.C.S., Rutgers Cancer Institue of New Jersey
1:05–1:15 pm	Crash Course Objectives Edmund C. Lattime, Ph.D., Rutgers Cancer Institute of New Jersey
1:15–1:45 PM	Understanding membrane-less organelles/condensates within living cells Clifford P. Brangwynne, Ph.D., Princeton University-Chemical and Biological Engineering, Howard Hughes Medical Institute
1:45–2:15 pm	Theory of associative polymers and implications for biomolecular condensates Rohit V. Pappu, Ph.D., Washington University St. Louis-Biomedical Engineering
2:15–2:45 pm	How RNA encodes properties of condensates Amy S. Gladfelter, Ph.D., University of North Carolina-Biology
2:45–3:15 pm	Break
3:15-3:45 pm	The conformational entropy of biopolymers in the dilute phase sculpts sequence-dependent phase boundaries Ned S. Wingreen, Ph.D., Princeton University-Molecular Biology
3:45-4:15 pm	Building a molecular model of Ras/Raf signaling in the control of cell proliferation Carla Mattos, Ph.D., Northeastern University-Chemistry and Chemical Biology
4:15-4:45 pm	How is phase behavior encoded in prion-like low-complexity domains? Tanja Mittag, Ph.D., St. Jude Children’s Research Hospital-Structural Biology
4:45-5:00 pm	Closing remarks and acknowledgements Stephen K. Burley, M.D., D.Phil.
SPONSORS:
iqb.rutgers.edu	cinj.org	cbe.princeton.edu